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Background: Vitiligo, also known as leukoderma, is an autoimmune pigmentary disorder of the skin and mucous membrane that is characterized by white patches in the body due to destruction of Melanocytes. Although the global prevalence of vitiligo is less than 1%, but in our daily clinical practice vitiligo is not so rare skin disorder.

Method: A boy of 14 years old presented with depigmented patches on face, on both ears, both arms, hands, both legs, feet and on back for last 6-7 years without any improvement. Through individualistic approach this case was cured by the medicine Sepia officinalis over a period of more than 2 years which is evident from the photographic documentation. The improvement criteria were assessed using the VASI, VETF, and DQLI assessment scales. According to the standards outlined in the HOM-CASE guidelines, this case was reported.

Result: This case was resolved after using Sepia officinalis, a homeopathic remedy, and no adverse effects were noted.
Conclusions: This case strongly supports the individualistic treatment approach, which is exclusive to homeopathy, in the field of evidence-based medicine. Therefore, the case’s conclusions may provide a foundation for future studies on the application of individualized homeopathic medicine to the management of vitiligo.

Keywords: Case Report, Individualized Homoeopathy, Vitiligo, Sepia officinalis.

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